Endocrinology Made Simple : Normal Functions Of Somatostatin

Normal Functions Of Somatostatin :

Somatostatin has following normal functions in human body:

1. Inhibit the release of growth hormone from Anterior pituitary gland

2. Inhibit the release of thyroid-stimulating hormone (TSH)

3. Suppression of release of following gastrointestinal hormones : Gastrin, Cholecystokinin          (CCK),Secretin,Motilin,Vasoactive intestinal peptide (VIP),Gastric inhibitory polypeptide (GIP),Enteroglucagon

4. Reducing the rate of gastric emptying, and

5. Reducing smooth muscle contractions and blood flow within the intestine

6. Suppressing the release of pancreatic hormones

7. Inhibiting the release of insulin and glucagon

8. Suppressing the exocrine secretory action of pancreas