Blisters arise due to separation of epidermal cells as a
result of one of the following phenomenon:
Allergic reaction
Trauma or injury
Infection
Oedema
Inflammation
Vasculitis
In addition,allergy causes immune reactions that ocuur at
junction of epidermis and dermis aand cause blister formation.
Predisposing Factors:
There is a high chance of blister formation in indivduals
with predisposition to allergy and there is an element of genetic
susceptibility as well.
Most common blistering disorders of the skin (also known as
immunobullous disorders are as follows:
Pemphigoid
Pemphigus
Dermatitis Herpetiformis
Linear IgA
General Principles Of Management :
Avoid precipitans
Topical treatment
Systemic Therapy including immunosuppressive drugs
Skin Blister
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