Causes of Peripheral Neuropathy

Causes of a Peripheral Neuropathy :

Predominantly sensory

Common causes include :

Diabetes mellitus

Alcohol

Drugs – eg isoniazid and vincristine

Vitamin deficiency eg B1 and B 12

Predominantly motor :

Guillain Barre Syndrome and Botulism – present acutely

Lead toxicity

Porphyria

HSMN : Hereditary Sensori Motor Neuropathy

Mononeuritis Multiplex

Diabetes

Connective Tissue Disease eg  SLE and Rheumatoid arthritis

Vasculitis eg  PAN  : Polyarteritis Nodosa and CSS Churg Strauss Syndrome

Infection eg HIV

Malignancy