Toxic Epidermal Necrolysis :
This is an extensive and life threatening skin
muco-cutaneous skin disorder that usually occurs in response to a use of
medication.
It causes extensive necrosis of skin and formation of
blisters and large part of skin becomes denuded.
Patients become unwell clinically and can lead to
dehydration and death rapidly if not treated in time.
Mucous membranes of eyes,mouth and genitalia can become
involved.
It shoud be treated in HDU prompltly.
The causative medications should be withdrawn.
Toxic Epidermal Necrolysis
Toxic Epidermal Necrolysis
Steven Johnson”s Syndrome
This is a immune complex mediated hypersensitivity reaction
to drugs that involves mucous membranes of mouth eyes and genitals .
Patients are clinically unwell with fever,headache,and malaise.
The skin lesions consist of erythema,pustules papules and
erosions.
Treatment consists of stopping the offending drugs,fluid
balance and skin dressings.
Incase of serious /extensive involvement,the patient should
be nursed in HDU
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